Description
AOD-9604 (also known as Tyr-hGH177-191 or AOD9604) is a synthetic hexadecapeptide (16 amino acids long) that constitutes a modified fragment of the C-terminal region (residues 177–191) of human growth hormone (hGH), with an additional tyrosine residue substituted at the N-terminus for enhanced stability. Its amino acid sequence is: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (YLRIVQCRSVEGSCGF), featuring a disulfide bridge between Cys⁷ and Cys¹⁴, forming a cyclic structure.
Chemically, it has the molecular formula C₇₈H₁₂₃N₂₃O₂₃S₂ and a molar mass of approximately 1815.10 g/mol (free base form; CAS 221231-10-3).
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